It’s evident that Osteoarthritis is a predominant
joint disease in India
Osteoarthritis (OA) is the most frequent joint disease with a prevalence of 22% to 39% in India
Nearly, 45% of women over the age of 65 years have symptoms
OA is the leading cause of disability in India affects over 15 million Indians each year
By 2020 the number of 65+ population in India is likely to be about 177 million
The most commonly used medications are NSAIDs, Injectable Corticosteroids, Dietary
Supplements (Cod Liver Oil, Glucosamine, Chondroitin)
Corticosteroids have a plethora of side effects like weight gain, skin rashes & weakness
Dietary supplements are only effective in mild cases
NSAIDs only help symptomatically and bring little to no improvement in functional disability
Despite all the available treatments in India, there’s barely a small section of Osteoarthritis patients who get access to them. Price and lack of awareness play contributing factors here as well. Clearly, there is a need for a solution that is effective, affordable and treats osteoarthritis from the root
Ayurveda has always had highly effective solutions for the treatment of conditions like Osteoarthritis. With its experience of over 9 decades and expertise in Ayurveda, AVN Ayurveda has researched and developed Zeotone Plus, an Ayurvedic medicine that is highly effective in treating Osteoarthritis. Understanding the lack of therapeutic options in conventional medicine and the need for scientifically proven solutions, we at AVN scientifically validated the product through a clinical trial conducted in partnership with a WHO-ICH-approved CRO & the results were remarkable. AVN Ayurveda is now looking at partnering with pharmaceutical companies to white-label the brand to increase its reach, thereby increasing the number of people who can benefit from this remarkable solution.
Envisioned and developed through treating and observing over 100000 patients in the last two decades.
Developed & validated in animal models for safety & efficacy.
Clinically validated through an extensive clinical trial conducted with a WHO approved CRO
Free from heavy metals
Clinically proven to be safe for long periods of consumption
A double-blind, prospective, multicentric, randomized, three-arm, clinical study to evaluate the efficacy, safety and
tolerability of polyherbal formulation Zeotone Plus in comparison with placebo and a formulation containing glucosamine and
chondroitin sulphate in the treatment of osteoarthritis in adult subjects was conducted.
Understanding the enormous revenue potential due to the huge market size for osteoarthritis medications
The market potential/size for Osteoarthritis globally is huge, over 1 in 5 people in India above the age of 55 suffer from Osteoarthritis. AVN Ayurveda, with it's limited doctor reach, was still able to sell over 4,000,000 capsules exclusively to AYUSH doctors in year 2 after launch. Pharmaceutical companies with greater doctor reach will have guaranteed sales due to the efficacy of the product, prevalence of indication & lack of effective alternative solutions.
in comparison to existing treatments
Understanding the enormous revenue potential due to the huge market size for osteoarthritis medications
| Description | Zeotone Plus | NSAIDs |
| Pain relief | Gradual pain relief - more than 70% in 90 days | Rapid pain relief |
| Recurrence of pain | Recurrence of pain not seen for over 4 months after therapy | Recurrence of pain on stopping dosage |
| Functional disability | Proven to decrease functional disablity by over 36% | Not prove to decrease functional disability |
| Mode of Action | Works as both Anti-inflammatory & Anti-degenerative & thereby helps reverse the disease condition | Anti-inflammatory - only reduces inflammation during period of use, does not help reverse the disease condition |
| Safety | Scientifically proven to be safe for long periods of treatment | Scientifically proven to be UNSAFE for prolonged use |
| Side effects | No adverse events reported during the course of the study | Renal function impairements, Hepatic function impairments on long term use |
| Ease of use | Easy to swallow capsules - 2 capsules twice daily | Usually used SOS, not suitable for prolonged use |
We are committed to ‘keeping India moving’ by bringing forth the latest advances in Ayurveda based
on extensive R & D in our homegrown infrastructure.
AYUSH practitioners depend on AVN Ayurveda
for their clinical practise
Years of Legacy
Osteoarthritis patients consulted and
managed over 2 decades
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Zeotone Plus® was 40% more effective than glucosamine and chondroitin in the management of osteoarthritis
